Charles Of_valois …, son of John Of_valois …. He married Louise Of_savoy …. She was born in 1476 and died in 1531 at the age of 55.

Francis_i …, son of Charles Of_valois … and Louise Of_savoy …, was born on September 12, 1494 in Cognac, France and died on March 31, 1547 in Rambouillet, France at the age of 52. He married 2 times. The first time he married Claude Of_france …, daughter of Louis_xii … and Anne Of_brittany …, on May 18, 1514. She was born in 1499 and died in 1524 at the age of 25. The second time he married Eleanor …, daughter of Philip_i The_handsome … and Joanna The_mad (Juana) …, on July 8, 1530. She was born in 1498 and died in 1558 at the age of 60.

Madeleine Of_france …, daughter of Francis_i … and Claude Of_france …. She died in 1537. She married James_v Stuart, son of James_iv Stuart and Margaret Tudor,. He was born in 1512 in Linlithgow, , Scotland and died in 1542 in Falkland Palace, Fife, Scotland at the age of 30.

Henry_ii …, son of Francis_i … and Claude Of_france …, was born on March 31, 1519 in Saint-Germain, En-Laye and died on July 10, 1559 in Paris, France at the age of 40. He married Catherine Of_florence De_medici on October 28, 1533. She was born in 1519 and died in 1589 at the age of 70.